I've been to the UK before, but only in short spurts. I am just wrapping up a month-long visit, and during my stay, I have compiled a list of differences between English and American speech. I've had quite a laugh over some of the uses and pronunciations, and so, without further ado...

English American
  • Holiday vs Vacation
  • Chips vs Fries
  • Crisps vs Chips
  • Garden vs Backyard
  • Lorry vs Truck
  • Trolly vs Cart (as in a shopping cart)
  • Knickers/Pants vs Underwear
  • Loo/Toilet vs Bathroom/Restroom
  • Let vs Rent
  • Biscuit vs Cookie
  • Torch vs Flashlight
  • Vitamin (pronounced with a soft "i" as in "big") vs Vitamin (pronounced with a hard "i", as in "bike")
  • Drink Driving vs Drunk Driving
  • Boot vs Trunk
  • Nappy vs Diaper
  • Swimming Costume vs Swimsuit
  • Boots vs Shoes (specifically athletic)
  • Cling Film vs Saran Wrap/Plastic Wrap
  • Sun Cream vs Sunblock/Sunscreen
  • Pupil vs Student
  • Vest vs Undershirt (specifically the one with no sleeves, ala the "wifebeater" style)
  • Queue (how many vowels can we put in succession in a word?) vs Line
  • Fillet (ignore the French pronunciation and say it just like it is spelled: Fill-et) vs Filet (pronounce it like the French intended: Fil-lay)
  • Jalapeņo (ignore the Spanish pronunciation and say it just like it is spelled: Jal-a-pee-no) vs Jalapeņo (pronounce it like the Spanish intended: Hal-a-pen-yo)

I'm sure there is more, so feel free to add to the list.